Concerta (Methylphenidate) 36mg
Concerta (Methylphenidate) 36mg
The device, which looks like a regular tablet, comprises an immediate-release drug coating and a semipermeable membrane that encircles an osmotically active trilayer core.The trilayer core is made up of a push layer with osmotically active ingredients and two drug layers that hold the medicine and excipients. The tablet’s drug-layer end has a precisely laser-drilled opening. The medication coating dissolves in an hour in a watery environment, like the gastrointestinal tract, and delivers a starting dose of methylphenidate. Water seeps into the tablet core through the membrane. By expanding the osmotically active polymer excipients, the aperture allows methylphenidate to be released. Drug distribution is regulated by the membrane, which also governs the pace at which water enters the tablet core.
Additionally, the drug-concentration gradient built into the two drug layers of CONCERTA® causes the drug release rate from the system to increase throughout 6 to 7 hours. Together with the insoluble core components of the tablet, the biologically inert components of the tablet stay whole during gastrointestinal transit and are expelled in the stool as a tablet shell. It is possible that, in some instances, mainly when digital enhancing techniques are applied, CONCERTA® extended-release tablets will appear on abdominal X-rays.




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