Darvocet-A500 (Acetaminophen & Propoxyphene) 100/500 mg

Description

Darvocet-A500 (Acetaminophen & Propoxyphene) 100/500 mg

Propoxyphene Napsylate, USP is an odorless, white crystalline solid with a bitter taste. It is very slightly soluble in water and soluble in methanol, ethanol, chloroform, and acetone. Chemically, it is ((alpha) S , 1 R )-(alpha)-[2-(Dimethylamino)-1-methylethyl]-(alpha)-phenylphenethyl propionate compound with 2-naphthalene-sulfonic acid (1:1) monohydrate, which can be represented by the accompanying structural formula:https://theodora.com/drugs/darvocet_a_500_tablets_xanodyne.html

Darvocet-A500 (Acetaminophen & Propoxyphene) 100/500 mg

Propoxyphene is a centrally acting narcotic analgesic agent. Equimolar doses of propoxyphene hydrochloride or napsylate provide similar plasma concentrations. Following administration of 65, 130, or 195 mg of propoxyphene hydrochloride, the bioavailability of propoxyphene is equivalent to that of 100, 200, or 300 mg respectively of propoxyphene napsylate. At or near therapeutic doses, this absorption difference is small when compared with that among subjects and among doses.https://www.familyfarepharmacy.net/

Propoxyphene is a mild narcotic analgesic structurally related to methadone. The potency of propoxyphene napsylate is from two thirds to equal that of codeine.

Darvocet A500™ provides the analgesic activity of propoxyphene napsylate and the antipyretic-analgesic activity of acetaminophen.

The combination of propoxyphene and acetaminophen produces greater analgesia than that produced by either propoxyphene or acetaminophen administered alone.

 

INDICATIONS AND USAGE

This product is indicated for the relief of mild to moderate pain, either when pain is present alone or when it is accompanied by fever.

 

CONTRAINDICATIONS

Hypersensitivity to propoxyphene or acetaminophen.