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The dosage will be determined by your medical condition and reaction to treatment. It is always advisable to follow the specified dosage, frequency, and duration of pharmaceutical usage. As directed, cease using the medication.When pain medication is used as soon as it occurs, the best outcomes are achieved. If you wait until the pain gets worse, the medication might not work as well.If you suffer from chronic pain, such as that brought on by cancer, your doctor may suggest that you additionally take long-acting opioid medications. If so, this medication might only be prescribed in extreme cases to relieve sudden (breakthrough) pain. Additionally, this medication may be used in addition to other painkillers (such acetaminophen).