Sublimaze (Fentanyl Citrate) 50mcg/ml injection

SUBLIMAZE (fentanyl citrate) Injection is an extremely effective narcotic analgesic. Each milliliter of solution includes fentanyl citrate equivalent to 50 mcg of fentanyl basic, pH adjusted with sodium hydroxide to 4.0 to 7.5. SUBLIMAZE has a molecular weight of 528.60 and is chemically characterized as N-(l-phenethyl-4-piperidyl) propionanilide citrate (1:1). The empirical equation is C22H28N20•C6H807. SUBLIMAZE’s structural formula is

Fentanyl’s respiratory depressive impact, like that of other powerful opioids, may last longer than the observed analgesic effect. Before ordering opioid analgesics after recovery from anesthesia, the practitioner should evaluate the overall dose of all opioid agonists provided.

If Fentanyl Citrate Injection is combined with a CNS depressant, learn about the qualities of each medicine, notably the duration of action of each product. Furthermore, when such a combination is taken, fluids and other hypotension-management countermeasures should be provided [see WARNINGS AND PRECAUTIONS].

When the solution and container allow, visually inspect parenteral medication products for particle matter and discoloration before administration.

Indications and Dosage

Information on Drugs

DESCRIPTION

SUBLIMAZE (fentanyl citrate) Injection is a powerful narcotic analgesic. Each milliliter of solution contains fentanyl citrate equivalent to 50 mcg of fentanyl basic, with the pH adjusted to 4.0 to 7.5 with sodium hydroxide. The chemical formula for SUBLIMAZE is N-(l-phenethyl-4-piperidyl) propionamide citrate (1:1). The empirical formula is C22H28N20•C6H807. The structural formula for SUBLIMAZE is as follows:

The structural formula for ZOCOR (simvastatin) is depicted.

SUBLIMAZE is a sterile, non-pyrogenic, preservative-free aqueous solution for intravenous or intramuscular injection.

Indications and Dosage

INDICATIONS

The following conditions are treated with Fentanyl Citrate Injection:

Analgesic activity with a short half-life during anesthesia, premedication, induction, and maintenance, and as needed in the early postoperative period (recovery room).

use as a narcotic analgesic additive in general