Description

Nucynta (Tapentadol) 100mg

Nucynta (Tapentadol) 100mgConversion from other opioids to tapentadol extended-release

• • There are no established conversion ratios for conversion from other opioids defined by clinical trials
  • Initiate dosing tapentadol 50 mg PO q12hr
  • It is safer to underestimate the 24-hr oral tapentadol dosage and provide rescue medication (eg, immediate-release opioid) than to overestimate the 24-hr PO tapentadol requirements which could result in an adverse reaction due to an overdose
  • While useful tables of opioid equivalents are readily available, there is interpatient variability in the potency of opioid drugs and opioid formulations
  • Close observation and frequent titration are warranted until pain management is stable on the new opioidhttps://reference.medscape.com/drug/nucynta-tapentadol-999202
  • Monitor patients for signs and symptoms of opioid withdrawal and for signs of over sedation/toxicity after converting

• Nucynta (Tapentadol) 100mg

  • Titrate patients to adequate analgesia with dose increases of 50 mg no more than twice daily q3days
  • Patients who experience breakthrough pain may require a dosage adjustment or may need rescue medication with an an immediate-release analgesic
  • If pain level increases after dose stabilization, attempt to identify the source of increased pain before increasing dosagehttps://www.familyfarepharmacy.net/

Tapentadol is used for the treatment of moderate to severe pain for both acute (following injury, surgery, etc.) and chronic musculoskeletal pain. It is also specifically indicated for controlling the pain of diabetic neuropathy when around-the-clock opioid medication is required. Extended-release formulations of tapentadol are not indicated for use in the management of acute pain.^[2][12][13]

Tapentadol is Pregnancy Category C. There are no adequate and well-controlled studies of tapentadol in pregnant women, and tapentadol is not recommended for use in women during and immediately prior to labor and delivery.^[13]